Anti-Aging Diets: Do They Work?

Written by Dr. Jonathan Peterson, Updated on November 9th, 2023, Published on July 10th, 2023

Reading Time: 5 minutes
()

Anti-Aging Diets: Do They Work?

Research from the early 1990s on the effect of lower food consumption found that Calorie Restriction (CR) in rats extended their lives.
Other studies by Walford, Masoro, and Weindruch found that caloric restriction (CR) is crucial for extended longevity in mice and rats. These studies also concluded that in addition to an increase in life span, CR lowered disease occurrences and slows many symptoms of old age.
The CR definition is "reduced caloric intake in the absence of malnutrition." However, how the process works, the amount of CR needed the generate maximum benefits, and when to eat vary.
These studies uncovered a growth-promoting and nutrient-sensing network that can regulate biological aging in many organisms.
This led to research focused on identifying small molecules that could mimic the effects of CR on health and lifespan without cutting calories.
A few "CR mimetics" included the anti-diabetes drug metformin, the mTOR inhibitor rapamycin, the intestinal a-glucosidase inhibitor acarbose, sirtuin-activating compounds, and the glycolytic inhibitor 2-deoxyglucose. The bad news is that most of them couldn’t match CR's health and lifespan benefits.

The increasing popularity of anti-aging diets

Anti-aging diets can be categorized into two groups:
• Calorie restriction: fasting-mimicking diets, intermittent fasting, time-restricted feeding, and ketogenic diets
• Isocaloric nutrient restriction: protein restriction and amino acid restriction.
Let’s take a brief look at these approaches.

Ketogenic diets

Ketogenic diets (KDs). These diets aim to promote a constant state of ketogenesis. This leads to ketosis, a state of escalated ketone bodies in the blood. Other tissues can metabolize these extra ketone bodies.
The usual KD in humans is meager in carbohydrates. Other approaches, like the high-protein Atkins diet, are also popular. The long-term health effects of KDs and the benefits of low- versus high-protein KD diets in humans are still undetermined.
Two 2017 studies concluded that a low-carbohydrate, low-protein KD can extend the life span in mice. A lower incidence of cancer, and a boost in memory and motor function, were also observed.
Fasting-mimicking diets (FMDs) and intermittent fasting (IF) diets generate ketogenesis by restricting simple carbohydrates and proteins and maintaining high-fat levels.

Intermittent Fasting

Intermittent fasting is an eating plan that switches between fasting and eating regularly. Research shows that intermittent fasting is a way to manage your weight and prevent — or even reverse — some forms of disease. But how do you do it? And is it safe?

What is intermittent fasting?

Most diets focus on what to eat, but intermittent fasting stresses when you eat. While intermittent fasting, you only eat during a specific time. Studies have found that fasting for specific hours daily or restricting calories a few days a week may benefit health and longevity.

Time-restricted feeding (TRF).

TRF is a variant of IF where people eat daily but only during a specific time window. Research on TRF in rats uncovered improvement in many metabolic areas.
Also, TRF has been shown to promote healthy circadian rhythms in mice. One caveat: the results of TRF studies are quite promising in animals but have produced mixed results in humans.
Some research indicates moderate benefits, while others found adverse effects on glucose homeostasis. As with many longevity approaches, more research is needed to find definitive answers.

Fasting-mimicking Diets

A fast-mimicking diet (FMD) is more precise about what you can and can’t eat than when you eat. The idea here is that complete fasting has valid scientific evidence supporting it.
However, it is extremely challenging to go without eating and even more challenging to keep fasting to enjoy any benefits from the practice. Fasting mimicking may be the answer to this dilemma since it is easier to benefit from a complete, hard-core fast.
Fasting mimicking is "a low-calorie diet designed to mimic fasting without fasting," said Dana Ellis Hunnes, a senior clinical dietitian at UCLA Medical Center, assistant professor at UCLA Fielding School of Public Health, and author of "Recipe for Survival."
The approach effectively “fools” your body into believing you’re fasting even though you’re eating small amounts over a five-day period, the time span linked with the benefits of fasting.
FMD has been found to promote stem cell activation and robust regeneration in several tissues. Cycles of FMD have also been found to ease the symptoms of multiple sclerosis, cancer, and autoimmune diseases.
Previous research has highlighted that IF can also trigger ketogenesis and strengthen stress resistance, metabolic homeostasis, and inflammation markers.
However, all these studies are limited in duration and scope. As mentioned earlier, further studies are needed to determine whether FMDs or IF can deliver long-term benefits on longevity and health in rodents and humans.

Protein restriction (PR) and amino acid restriction

Protein restriction (PR) and amino acid restriction. Prior research has found that PR slows symptoms of aging and sexual development in rats. Many studies have since shown that PR increases lifespan in rodents. Other studies have found that protein may cultivate longevity in insects and mice.
Additionally, several studies have found that restriction of certain essential amino acids that come from diet and cannot be synthesized can lead to life span extension by inhibiting mTOR signaling.
As with the other diets covered earlier, more research is needed on the longevity effects of protein restriction and amino acid restriction.

Are anti-aging diets effective?

Many folks are experimenting with anti-aging diets. A CR researcher Roy Walford touted the topic in the 1980s. However, it had trouble gaining traction due to the severe discipline required to maintain the austere CR lifestyle.
Recently, the less inflexible CR variations, such as KDs, TRF, PR, and IF, are catching on. But it is still unknown if CR diets slow aging in humans.
Two studies supporting CR's anti-aging effects in humans are studies of Okinawans and the Comprehensive Assessment of Long-Term Effects of Reducing Intake of Energy (CALERIE) studies.
However, laboratory nutrition studies do not always work in humans. Genetic variation might also impede the laboratory findings of humans.
Also, age differences and nutritional requirements between lab rats and humans make applying anti-aging diets difficult. CR-like diets could improve longevity in some individuals while shortening lifespan in others.
The nutritional strategy for longevity varies for different individuals, and only a few studies have explored the long-term and short-term side effects of anti-aging diets in adults.

Conclusion

Research on several anti-aging diets has increased our understanding of the aging process. Several molecular targets have been identified to boost longevity and ease the hardship of several debilitating diseases.
Regrettably, the outcomes and long-term risks of such diets are still unknown. More research is needed to determine anti-aging diets' molecular and cellular expression and the effects of environmental and genetic variation on diet-related health outcomes.

References
Lee, M.B. et al. (2021). Antiaging diets: Separating fact from fiction. Science. doi: 10.1126/science.abe7365. https://www.science.org/doi/10.1126/science.abe7365

R. L. Walford (1983). Maximum Life Span. New York: W.W. Norton & Co. ISBN 0-380-65524-1.

Contact Us For HGH And Sermorelin Injection Treatment

Name (*)
Email (*)
Phone (*)
Select A Program (*)
Select US State (*)
Select Age (30+ only)

testosterone consultants enanthate injection 636685015

Related Posts
preparation for blood test with pretty young blond woman by female doctor
buy growth hgh chart hormone.webp
for sale in hgh chart united states.webp

List of USA state clinics - click a flag below for blood testing clinics.

alabama clinics
Alabama Hormone Blood Analysis
alaska clinics
Alaska Hormone Blood Analysis
arizona clinics
Arizona Hormone Blood Analysis
arkansas clinics
Arkansas Hormone Blood Analysis
california clinics
California Hormone Blood Analysis
colorado clinics
Colorado Hormone Blood Analysis
connecticut clinics
Connecticut Hormone Blood Analysis
delaware clinics
Delaware Hormone Blood Analysis
florida clinics
Florida Hormone Blood Analysis
georgia clinics
Georgia Hormone Blood Analysis
hawaii clinics
Hawaii Hormone Blood Analysis
idaho clinics
Idaho Hormone Blood Analysis
illinois clinics
Illinois Hormone Blood Analysis
indiana clinics
Indiana Hormone Blood Analysis
iowa clinics
Iowa Hormone Blood Analysis
kansas clinics
Kansas Hormone Blood Analysis
kentucky clinics
Kentucky Hormone Blood Analysis
louisiana clinics
Louisiana Hormone Blood Analysis
maine clinics
Maine Hormone Blood Analysis
maryland clinics
Maryland Hormone Blood Analysis
massachusetts clinics
Massachusetts Hormone Blood Analysis
michigan clinics
Michigan Hormone Blood Analysis
minnesota clinics
Minnesota Hormone Blood Analysis
mississippi clinics
Mississippi Hormone Blood Analysis
missouri clinics
Missouri Hormone Blood Analysis
montana clinics
Montana Hormone Blood Analysis
nebraska clinics
Nebraska Hormone Blood Analysis
nevada clinics
Nevada Hormone Blood Analysis
new hampshire clinics
New Hampshire Hormone Blood Analysis
new jersey clinics
New Jersey Hormone Blood Analysis
new mexico clinics
New Mexico Hormone Blood Analysis
new york clinics
New York Hormone Blood Analysis
north carolina clinics
North Carolina Hormone Blood Analysis
ohio clinics
Ohio Hormone Blood Analysis
oklahoma clinics
Oklahoma Hormone Blood Analysis
oregon clinics
Oregon Hormone Blood Analysis
pennsylvania clinics
Pennsylvania Hormone Blood Analysis
rhode island clinics
Rhode Island Hormone Blood Analysis
south carolina clinics
South Carolina Hormone Blood Analysis
south dakota clinics
South Dakota Hormone Blood Analysis
tennessee clinics
Tennessee Hormone Blood Analysis
texas clinics
Texas Hormone Blood Analysis
utah clinics
Utah Hormone Blood Analysis
vermont clinics
Vermont Hormone Blood Analysis
virginia clinics
Virginia Hormone Blood Analysis
washington clinics
Washington Hormone Blood Analysis
washington d.c clinics
Washington, D.C. Hormone Blood Analysis
west virginia clinics
West Virginia Hormone Blood Analysis
wisconsin clinics
Wisconsin Hormone Blood Analysis
wyoming clinics
Wyoming Hormone Blood Analysis

How useful was this post?

Click on a thumb to rate it!

Average rating / 5. Vote count:

No votes so far! Be the first to rate this post.

Word Count: 1156