Side Effects and Risks Associated with HGH Therapy | Ensuring Safe Treatment

Written by Dr. Jonathan Peterson, Updated on September 16th, 2021
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Always talk to your physician about any issues you are experiencing while on HGH!


Most people have a rather simple understanding of Human Growth Hormone (HGH). They understand that HGH is important for growth and development without understanding the more complex effects of HGH, especially with regard to health and wellness maintenance during adulthood. There's a sense that Growth Hormone is capable of some really marvelous things, because people are aware that HGH has been used by athletes and other professionals in the past. However, allow us to go into more depth regarding the widespread effects of Human Growth Hormone, as well as the risks associated with Human Growth Hormone therapy and abuse.

Potential Side Effects of Human Growth Hormone Injection Therapy

Remember that, realistically, no drug comes without at least a minor risk of side effects. Using bio-identical HGH does come with some risks that you should be aware of.

The following are minor side effects that you may experience:

  • Sometimes HGH injections can cause slight numbness or tingling of the skin, specifically around the injection site.
  • Injections can also cause soreness and irritation around where injections are administered. Rotating injection sites frequently reduces this risk.

The following are symptoms that you may experience as a result of therapeutic HGH therapy. Talk to your doctor if you experience the following:

  • Swelling and Water Retention
  • Digestive Distress
  • Increased Cholesterol

Talk to your doctor about any medications that you may be taking, whether prescription or over the counter. HGH therapy may interact with certain medications.

HGH Abuse Side Effects

Many side effects are generally the result of HGH abuse. Never use recombinant Human Growth Hormone therapy without a valid reason or without the express consent of a Hormone Doctor or other qualified medical physician. If you abuse Growth Hormone, there is a real chance you may experience the following issues:

  • Acromegaly,  which is the abnormal growth of cartilage and bone, especially those of the face, jaw, hands and feet
  • Coarse skin, caused by enhanced division rate of skin cells
  • Carpal Tunnel Syndrome
  • Joint growth
  • Deepening of the voice due to larynx growth
  • Arthritis

Cancer Risk with HGH Therapy?

Human Growth Hormone should not be used by patients suffering from cancer, because HGH injections work by facilitating cellular division, and this may impact the rate at which certain cancers develop. This is why thorough screening is necessary before Growth Hormone therapy begins, and why annual or semi-annual checkups are a necessary requirement while taking HGH shots.

Interested in HGH Therapy? Our Hormone Specialists are standing by!

In Spite of the Risks, There's Lots of Great Things about HGH

It makes sense that, after looking over the potential risks associated with Growth Hormone shots, you may experience a bit of apprehension. This is healthy and natural. It's important that before you undergo any Hormone Regimen or other medical treatment that you have a full grasp of the downsides associated with that treatment. On the other hand, you shouldn't let that dissuade you from utilizing the amazing potential of bio-identical Human Growth Hormone therapy to revitalize your life. Remember that most of the serious risks are associated with the misuse and abuse of HGH. Most people that experience major issues take way too much Human Growth Hormone, or use it when their bodies don't need it.

If you get a legal prescription from a board-certified physician, and you follow his or her directions and guidelines, the risk of experiencing the worst HGH side effects decline dramatically, significantly improving the safety profile and the cost-risk ratio associated with treatment. Most HGH therapy regimens have a 5-on 2-off approach, meaning that you'll inject your HGH shot five times per week and rest for two days. This also helps prevent side effects.

On the off-chance that you experience side effects even when taking your medication conscientiously, your Hormone Specialist will be able to mitigate those symptoms under most circumstances, allowing you to continue therapy. When caught early, the risk of long-term issues relating to your Hormone Regimen is exceedingly rare.

At our licensed and board-certified Hormone and Anti-aging Clinic, we go to great lengths and take great pains to ensure that your Hormone Therapy is both right for you and safe for you. When you come to us for treatment, we require you to go through a physical and provide a blood sample so that we can thoroughly evaluate your health at the deepest levels. We'll also learn about your activity level and eating habits, along with any past health issues that you've had and any medications that you may be taking.

Our Hormone and Wellness Programs are designed specifically for the individual patient to both maximize the benefits and minimize the risks. We won't let you down.

Titrating Dosage to Maximize Safety

Another thing that we do to ensure that you take well to treatment is that we start with a low-dose of bio-identical Growth Hormone, and work our way up to a full therapeutic dosage after we get results back that show your body is responding appropriately to therapy. Furthermore, regular evaluations, once every six months to one year, will allow us to keep tabs on your endogenous Growth Hormone levels and let us know if we need to adjust the dosage to streamline your Hormone Replacement Therapy (HRT) treatment.

Real Prescription HGH -- Buying Illegally is a Recipe for Danger

Because human growth hormone has been so popular with athletes, such as professional sports athletes, bodybuilders and weight lifters in general, more and more (mostly) men are seeking the hormone on the black market. It seems that not many people want to try a physician-monitored program either, which is the safest option, if they have a legitimate need (which is the only reason you should be using it in the first place). Perhaps they believe they are saving money in the long run. However, the real danger here is not in regards to your wallet with illegal HGH, but with your health and hormone imbalance. If HGH is not taken under doctor supervision, there is a real risk to your overall health because the endocrine system is so sensitive and complex.

When you get a prescription from a licensed endocrinologist or hormone replacement therapy (HRT) clinic, it ensures that your therapy will be more successful and the risks of the treatment are greatly lowered. Our clinic partners with reputable pharmacies, including online, that will provide patients with high quality products that are what they say they are. The HGH that is used for HRT is very fragile and demands very special handling and care in order to retain potency. If you get your human growth hormone off the black market, you have no idea whether it was handled properly with the care needed for it to even work for you.

In addition, there is always the risk of not even receiving what you asked for. How do you know if what is in your vial is really HGH? Or  that it hasn't been cut or contaminated with other product...one that could potentially harm you? To be honest, the risks of black market HGH vastly outweigh the benefits of it. It is best to get your HGH from a qualified doctor rather than risk your health or jail time over it.

Improving Pituitary Health with Human Growth Hormone Therapy

Working with a doctor while taking HGH on a hormone replacement therapy program also ensures that your endocrine system remains healthy and functioning. Instead of you trying to figure out an injection schedule, we do this for you and we choose one that will keep the pituitary gland functioning properly, still able to produce growth hormone itself and not shutting the somatotrophs down that naturally create growth hormone.

In doing so, it prevents a condition called tachyphylaxis from occurring where basically, the body responds less and less to the HGH therapy with each successive dosage. We still want the pituitary gland to function on its own because once HGH therapy is stopped, issues could arise where the pituitary cannot manufacture HGH efficiently for awhile.

Most patients will take inject HGH five days out of the week, typically just before bed or in the morning after getting up. Two days out of the week, there will be no injections. This is the injection schedule that our clinic has found the most success with and the standard schedule that we use or build off of.

Always Be Honest With Your Provider!

Just like with any other therapy, procedure or treatment protocol, you must be honest and truthful with your doctor about everything having to do with your therapy, even the negative aspects of it. You may be seeing some amazing benefits, and do not want to stop the therapy, but if you fail to report any negative side effects, it may be worse for you in the long run. This is risky. You should always tell your doctor about any side effects so that treatment can be modified in order to protect your health and safety.

We must repeat that if you are currently suffering from cancer or have a past history with it, there is a risk to undergoing HGH therapy. In addition, this or other health issues may disqualify you from HGH therapy. Sorry to say, but this is another reason to be truthful with your doctor during your initial visit and discussion. Serious issues can develop in patients who are at high-risk for cancer or recurrence of any cancer.

We Take All the Necessary Precautions to Safeguard Your Wellness and Health

Our Hormone and Longevity Treatment Center is highly experienced in the treatment of Hormone Imbalance and Deficiency, and we take all the steps necessary to make sure that you are a valid candidate for the HRT treatments that we offer. Your safety is of our utmost concern.

Our goal is to help our patients live longer and healthier lives through the use of Hormone Optimization, Hormone Replacement Therapy and other health, medical, and lifestyle regimens so that you can experience vitality and wellness deep into your golden years.

If you are interested in Human Growth Hormone therapy for HGH Deficiency or any of the other Hormone Regimens that we offer, we encourage you to reach out to us. We would love nothing more than to help you reach your maximum potential. We treat patients thirty years and older, and we offer our services to patients nationwide!

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