Side Effects and Risks Associated with HGH Therapy | Ensuring Safe Treatment

Written by Dr. Jonathan Peterson, Updated on April 18th, 2018

Always talk to your physician about any issues you are experiencing while on HGH!


Most people have a rather simple understanding of Human Growth Hormone (HGH). They understand that HGH is important for growth and development without understanding the more complex effects of HGH, especially with regard to health and wellness maintenance during adulthood. There's a sense that Growth Hormone is capable of some really marvelous things, because people are aware that HGH has been used by athletes and other professionals in the past. However, allow us to go into more depth regarding the widespread effects of Human Growth Hormone, as well as the risks associated with Human Growth Hormone therapy and abuse.

Potential Side Effects of Human Growth Hormone Injection Therapy

Remember that, realistically, no drug comes without at least a minor risk of side effects. Using bio-identical HGH does come with some risks that you should be aware of.

The following are minor side effects that you may experience:

  • Sometimes HGH injections can cause slight numbness or tingling of the skin, specifically around the injection site.
  • Injections can also cause soreness and irritation around where injections are administered. Rotating injection sites frequently reduces this risk.

The following are symptoms that you may experience as a result of therapeutic HGH therapy. Talk to your doctor if you experience the following:

  • Swelling and Water Retention
  • Digestive Distress
  • Increased Cholesterol

Talk to your doctor about any medications that you may be taking, whether prescription or over the counter. HGH therapy may interact with certain medications.

HGH Abuse Side Effects

Many side effects are generally the result of HGH abuse. Never use recombinant Human Growth Hormone therapy without a valid reason or without the express consent of a Hormone Doctor or other qualified medical physician. If you abuse Growth Hormone, there is a real chance you may experience the following issues:

  • Acromegaly,  which is the abnormal growth of cartilage and bone, especially those of the face, jaw, hands and feet
  • Coarse skin, caused by enhanced division rate of skin cells
  • Carpal Tunnel Syndrome
  • Joint growth
  • Deepening of the voice due to larynx growth
  • Arthritis

Cancer Risk with HGH Therapy?

Human Growth Hormone should not be used by patients suffering from cancer, because HGH injections work by facilitating cellular division, and this may impact the rate at which certain cancers develop. This is why thorough screening is necessary before Growth Hormone therapy begins, and why annual or semi-annual checkups are a necessary requirement while taking HGH shots.

Interested in HGH Therapy? Our Hormone Specialists are standing by!

In Spite of the Risks, There's Lots of Great Things about HGH

It makes sense that, after looking over the potential risks associated with Growth Hormone shots, you may experience a bit of apprehension. This is healthy and natural. It's important that before you undergo any Hormone Regimen or other medical treatment that you have a full grasp of the downsides associated with that treatment. On the other hand, you shouldn't let that dissuade you from utilizing the amazing potential of bio-identical Human Growth Hormone therapy to revitalize your life. Remember that most of the serious risks are associated with the misuse and abuse of HGH. Most people that experience major issues take way too much Human Growth Hormone, or use it when their bodies don't need it.

If you get a legal prescription from a board-certified physician, and you follow his or her directions and guidelines, the risk of experiencing the worst HGH side effects decline dramatically, significantly improving the safety profile and the cost-risk ratio associated with treatment. Most HGH therapy regimens have a 5-on 2-off approach, meaning that you'll inject your HGH shot five times per week and rest for two days. This also helps prevent side effects.

On the off-chance that you experience side effects even when taking your medication conscientiously, your Hormone Specialist will be able to mitigate those symptoms under most circumstances, allowing you to continue therapy. When caught early, the risk of long-term issues relating to your Hormone Regimen is exceedingly rare.

At our licensed and board-certified Hormone and Anti-aging Clinic, we go to great lengths and take great pains to ensure that your Hormone Therapy is both right for you and safe for you. When you come to us for treatment, we require you to go through a physical and provide a blood sample so that we can thoroughly evaluate your health at the deepest levels. We'll also learn about your activity level and eating habits, along with any past health issues that you've had and any medications that you may be taking.

Our Hormone and Wellness Programs are designed specifically for the individual patient to both maximize the benefits and minimize the risks. We won't let you down.

Titrating Dosage to Maximize Safety

Another thing that we do to ensure that you take well to treatment is that we start with a low-dose of bio-identical Growth Hormone, and work our way up to a full therapeutic dosage after we get results back that show your body is responding appropriately to therapy. Furthermore, regular evaluations, once every six months to one year, will allow us to keep tabs on your endogenous Growth Hormone levels and let us know if we need to adjust the dosage to streamline your Hormone Replacement Therapy (HRT) treatment.

Real Prescription HGH -- Buying Illegally is a Recipe for Danger

With all of the talk about HGH as an agent of performance enhancement, there's a real temptation for people to go out and find HGH on the black market. There are also those that want to bypass the process of Physician-Mediation, whether to save money or for other reasons. There is a reason why HGH should only be taken with a doctor's permission and with a doctor's guidance -- HGH can be dangerous when used incorrectly or when used when not needed.

Working through a licensed Hormone Clinic or qualified doctor both ensures your treatment works and minimizes the risk of harm. We work with reputable pharmacies that provide HRT products of the highest quality, controlled heavily for safety and efficacy. Bio-identical HGH requires specific handling instructions to retain potency, and there's no guarantee that black market HGH has been treated with the care necessary to preserve its potency.

Furthermore, there is no guarantee that your product hasn't been tainted or cut with other compounds, or that the product you receive is even real Growth Hormone. Along with the legal ramifications of black market Growth Hormone, the risks simply outweigh the benefits by a tremendous amount.

Promoting Pituitary Function with HGH Therapy

One of the important things that we do when we  establish an HGH-RT Regimen is that we create an injection schedule that allows the pituitary gland to still produce its own Growth Hormone and prevents the Somatotrophs, cells which produce endogenous HGH, from shutting down. This helps promote healthy HGH levels and prevent Tachyphylaxis (a condition where the patient responds less and less to a drug upon successive dosage) while also helping the pituitary bounce back if HGH injection therapy is ever suspended completely.

The majority of patients will take HGH injections five days per week, usually before bed or upon waking up, and will pause therapy two days per week. This is the most common recipe for success with Human Growth Hormone.

Be Honest with Your Hormone Doctor to Avoid Complications

As with any medical treatment, it's of the utmost importance that you be upfront and honest with your doctor about both the positives and the negatives of your HGH therapy. If you're experiencing some major benefits, it may be enticing to ignore the potential side effects that you're going through in order to continue treatment, but you must tell your Hormone Doctor about your side effects so that he or she may recalibrate your treatment or otherwise modify your Hormone Optimization Plan for your safety and well-being.

We must reiterate the potential risk of complications with regard to patients with a current or past history with cancer. There are health issues which may exclude you from consideration for HGH therapy, and you should be open and honest with your doctor during evaluation, because serious complications can arise for patients at high-risk for cancer or cancer recurrence.

We Take All the Necessary Precautions to Safeguard Your Wellness and Health

Our Hormone and Longevity Treatment Center is highly experienced in the treatment of Hormone Imbalance and Deficiency, and we take all the steps necessary to make sure that you are a valid candidate for the HRT treatments that we offer. Your safety is of our utmost concern.

Our goal is to help our patients live longer and healthier lives through the use of Hormone Optimization, Hormone Replacement Therapy and other health, medical, and lifestyle regimens so that you can experience vitality and wellness deep into your golden years.

If you are interested in Human Growth Hormone therapy for HGH Deficiency or any of the other Hormone Regimens that we offer, we encourage you to reach out to us. We would love nothing more than to help you reach your maximum potential. We treat patients thirty years and older, and we offer our services to patients nationwide!

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