Diabetes Treatment Semaglutide Helps Obese Patients Lose Weight

Written by Dr. Jonathan Peterson, Updated on November 24th, 2023, Published on March 12th, 2021

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Type-2 Diabetes is one of the most significant health risks in the United States, affecting millions of Americans over the age of forty. Obesity is one of the monumental risk factors for Type-2 Diabetes and is an epidemic in the country. By 2018, over 40% of Americans are categorized as obese, with over 9% considered severely obese.


Semaglutide Effective Drug to treat Type-2 Diabetes—Could It Be More?

Semaglutide was FDA-Approved for the treatment of Diabetes in 2017, and researchers are still working to increase our knowledge regarding the beneficial impacts of the treatment. Many patients without Diabetes may also benefit from Semaglutide.

While Semaglutide has proven useful at helping Type-2 Diabetes patients lose weight and improve Insulin Sensitivity, scientists also believe the medication may be helpful in the treatment of obesity even without diagnosed Diabetes. Recent Clinical Trials have sought to explore how Semaglutide helps obese patients lose weight in combination with a diet and exercise program.

Phase 3 Semaglutide Obesity Trial Shows Great Promise

The results of Phase 3 of this trial were recently printed in The New England Journal of Medicine. In the end, patients taking Semaglutide experienced a reduction of body weight averaging 14.9 percent after following injection and lifestyle protocols. Almost all patients experienced significant weight loss in this study. Half of the experimental group lost at least 15% body weight, and 86% lost at least 5%.

Aside from these excellent weight loss results, the patients were also determined to be less threatened by the risk of heart disease and diabetes. They also reported improved exercise output and heightened physical function.

If Semaglutide could help patients lose weight without risks that outweigh the benefits, it could be a boon for hundreds of millions of people worldwide. Obesity is one of the biggest risk factors for several dangerous conditions such as cancer, fatty liver disease, Type-2 Diabetes, and heart disease.

It also contributes heavily to forms of Hormone Imbalance such as Human Growth Hormone Deficiency and Low-T. As you can imagine, this huge collection of risks has a tremendous effect on average life expectancy for men and women struggling with obesity.

As of today, exercise and diet are the primary means to help patients overcome obesity. Medications are generally only offered after six months of ineffective efforts. While medications can aid patients in losing weight, they come with their own risks and drawbacks. There is some hope that Semaglutide could be safer than most other Obesity Treatments on the market today.

How Does Semaglutide Work?

Semaglutide is a form of Hormone Therapy. It's designed to perfectly simulate the function of the naturally occurring hormone GLP-1. This hormone is released by the digestive system after eating, and it helps to control satiety and reduce cravings and hunger.

The treatment had relatively few side effects. Around 4.5% of experimental patients quit the treatment resulting from gastrointestinal issues, most commonly diarrhea and nausea. Most patients that experienced these side-effects dealt with them only temporarily.

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