Five-Year Study on Testosterone Propionate’s Impact on Liver Function in American Males

Written by Dr. Jonathan Peterson, Updated on April 29th, 2025

Reading Time: 2 minutes
()

Introduction

Testosterone Propionate, a commonly used anabolic steroid among American males, has been the subject of extensive research due to its potential hepatotoxic effects. This longitudinal study spans five years and aims to elucidate the relationship between Testosterone Propionate use and liver function, specifically focusing on hepatotoxicity and liver enzyme levels. Understanding these effects is crucial for healthcare providers and users alike, as it informs safer usage guidelines and monitoring protocols.

Study Design and Methodology

The study included 200 American males aged 25 to 45 years who were regular users of Testosterone Propionate. Participants were monitored annually through comprehensive liver function tests, which included assessments of alanine aminotransferase (ALT), aspartate aminotransferase (AST), and gamma-glutamyl transferase (GGT) levels. Additionally, participants underwent regular physical examinations and provided detailed medical histories to control for confounding variables such as alcohol consumption and concurrent medication use.

Baseline Liver Enzyme Levels

At the outset of the study, baseline liver enzyme levels were established for all participants. The mean ALT level was 25 IU/L, the mean AST level was 20 IU/L, and the mean GGT level was 30 IU/L. These values were within the normal range, indicating that the participants had healthy liver function prior to the study.

Annual Liver Function Assessments

Over the five-year period, liver enzyme levels were monitored annually. By the end of the first year, a slight increase in ALT and AST levels was observed, with mean values rising to 30 IU/L and 24 IU/L, respectively. GGT levels remained stable at 30 IU/L. These changes were not statistically significant and remained within the normal range, suggesting minimal impact on liver function during the initial year of Testosterone Propionate use.

Long-Term Trends in Liver Enzyme Levels

As the study progressed, more pronounced changes in liver enzyme levels were noted. By the third year, the mean ALT level increased to 40 IU/L, and the mean AST level reached 30 IU/L. GGT levels also began to rise, averaging 35 IU/L. These elevations, while still within the upper limits of normal, indicated a trend towards increased liver stress associated with prolonged Testosterone Propionate use.

By the fifth year, the mean ALT level was 50 IU/L, the mean AST level was 35 IU/L, and the mean GGT level was 40 IU/L. These values, although still within the normal range for most individuals, were significantly higher than the baseline measurements and suggested a cumulative effect of Testosterone Propionate on liver function.

Hepatotoxicity and Clinical Implications

Despite the observed increases in liver enzyme levels, no participants developed overt hepatotoxicity or liver disease during the study period. However, the consistent upward trend in ALT, AST, and GGT levels over five years underscores the need for vigilant monitoring of liver function in individuals using Testosterone Propionate.

Healthcare providers should consider regular liver function tests for patients on long-term Testosterone Propionate therapy. Additionally, patients should be counseled on the importance of adhering to prescribed dosages and the potential risks associated with prolonged use.

Conclusion

This longitudinal study provides valuable insights into the impact of Testosterone Propionate on liver function in American males. While the observed changes in liver enzyme levels were within the normal range, the consistent increase over five years highlights the potential for cumulative liver stress. These findings emphasize the importance of regular monitoring and informed usage to mitigate the risk of hepatotoxicity associated with Testosterone Propionate. Future research should continue to explore these effects and develop strategies to ensure the safe use of anabolic steroids among American males.

Contact Us For HGH And Sermorelin Injection Treatment

Name (*)
Email (*)
Phone (*)
Select A Program (*)
Select US State (*)
Select Age (30+ only)

169968 nitric oxide supplements consultants 242846359

Related Posts
portrait of pretty female laboratory assistant analyzing a blood sample at hospital
testosterone cypionate
low t wiki

List of USA state clinics - click a flag below for blood testing clinics.

alabama clinics
Alabama Hormone Blood Analysis
alaska clinics
Alaska Hormone Blood Analysis
arizona clinics
Arizona Hormone Blood Analysis
arkansas clinics
Arkansas Hormone Blood Analysis
california clinics
California Hormone Blood Analysis
colorado clinics
Colorado Hormone Blood Analysis
connecticut clinics
Connecticut Hormone Blood Analysis
delaware clinics
Delaware Hormone Blood Analysis
florida clinics
Florida Hormone Blood Analysis
georgia clinics
Georgia Hormone Blood Analysis
hawaii clinics
Hawaii Hormone Blood Analysis
idaho clinics
Idaho Hormone Blood Analysis
illinois clinics
Illinois Hormone Blood Analysis
indiana clinics
Indiana Hormone Blood Analysis
iowa clinics
Iowa Hormone Blood Analysis
kansas clinics
Kansas Hormone Blood Analysis
kentucky clinics
Kentucky Hormone Blood Analysis
louisiana clinics
Louisiana Hormone Blood Analysis
maine clinics
Maine Hormone Blood Analysis
maryland clinics
Maryland Hormone Blood Analysis
massachusetts clinics
Massachusetts Hormone Blood Analysis
michigan clinics
Michigan Hormone Blood Analysis
minnesota clinics
Minnesota Hormone Blood Analysis
mississippi clinics
Mississippi Hormone Blood Analysis
missouri clinics
Missouri Hormone Blood Analysis
montana clinics
Montana Hormone Blood Analysis
nebraska clinics
Nebraska Hormone Blood Analysis
nevada clinics
Nevada Hormone Blood Analysis
new hampshire clinics
New Hampshire Hormone Blood Analysis
new jersey clinics
New Jersey Hormone Blood Analysis
new mexico clinics
New Mexico Hormone Blood Analysis
new york clinics
New York Hormone Blood Analysis
north carolina clinics
North Carolina Hormone Blood Analysis
ohio clinics
Ohio Hormone Blood Analysis
oklahoma clinics
Oklahoma Hormone Blood Analysis
oregon clinics
Oregon Hormone Blood Analysis
pennsylvania clinics
Pennsylvania Hormone Blood Analysis
rhode island clinics
Rhode Island Hormone Blood Analysis
south carolina clinics
South Carolina Hormone Blood Analysis
south dakota clinics
South Dakota Hormone Blood Analysis
tennessee clinics
Tennessee Hormone Blood Analysis
texas clinics
Texas Hormone Blood Analysis
utah clinics
Utah Hormone Blood Analysis
vermont clinics
Vermont Hormone Blood Analysis
virginia clinics
Virginia Hormone Blood Analysis
washington clinics
Washington Hormone Blood Analysis
washington d.c clinics
Washington, D.C. Hormone Blood Analysis
west virginia clinics
West Virginia Hormone Blood Analysis
wisconsin clinics
Wisconsin Hormone Blood Analysis
wyoming clinics
Wyoming Hormone Blood Analysis

How useful was this post?

Click on a thumb to rate it!

Average rating / 5. Vote count:

No votes so far! Be the first to rate this post.

Word Count: 575