Sildenafil: From ED to PAH, Raynaud’s, Altitude Sickness, and Neurological Uses
Reading Time: 3 minutesIntroduction to Sildenafil Sildenafil, commonly known by its brand name Viagra, has been a revolutionary medication since its approval by the FDA in 1998 for the treatment of erectile dysfunction (ED) in men. Its primary mechanism of action involves the inhibition of phosphodiesterase type 5 (PDE5), which leads to increased levels of cyclic guanosine monophosphate (cGMP), promoting smooth muscle relaxation... Read more »


