Striant TRT’s Impact on Dental Health: A Two-Year Study in American Males

Written by Dr. Jonathan Peterson, Updated on May 10th, 2025

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Introduction

The Striant Testosterone Buccal System is a novel method for testosterone replacement therapy (TRT) in men suffering from hypogonadism. This treatment involves the application of a testosterone-containing buccal tablet that adheres to the gum above the incisor, releasing testosterone over a 12-hour period. While the efficacy of Striant in improving testosterone levels is well-documented, its long-term effects on oral health have been a subject of concern. This article delves into a two-year study that specifically examines the influence of the Striant system on dental health in American males, focusing on oral hygiene practices and dental outcomes.

Study Design and Methodology

The study was conducted over a two-year period, involving 200 American males aged between 30 and 65 years who were prescribed the Striant Testosterone Buccal System for TRT. Participants were divided into two groups: those using Striant and a control group using alternative TRT methods. Both groups were monitored through regular dental check-ups, which included assessments of plaque buildup, gum health, and overall oral hygiene. Participants were also required to maintain a daily log of their oral hygiene practices, including frequency of brushing, flossing, and any issues experienced with the buccal system.

Findings on Dental Health

After two years, the study found no significant increase in dental issues such as gum disease or tooth decay among the participants using the Striant system compared to the control group. However, a notable observation was a slight increase in plaque buildup in the Striant group, particularly around the site of tablet application. This was attributed to potential interference with regular brushing and flossing routines, as participants reported difficulty in cleaning the area effectively.

Oral Hygiene Practices and Challenges

Participants using Striant reported a need for more diligent oral care routines to counteract the challenges posed by the buccal system. Many noted that the presence of the tablet made it difficult to brush and floss as thoroughly as they would without it. To address this, participants were advised to use a soft-bristled toothbrush and to gently clean the area around the tablet. The study emphasized the importance of regular dental visits and professional cleanings to maintain optimal oral health while using Striant.

Implications for Dental Care Professionals

Dental care professionals should be aware of the potential for increased plaque buildup in patients using the Striant Testosterone Buccal System. It is recommended that they provide tailored advice on oral hygiene practices to mitigate these risks. Additionally, patients should be educated about the importance of maintaining a rigorous oral care routine and the need for regular dental check-ups to monitor their oral health closely.

Patient Education and Compliance

Patient education plays a crucial role in the successful use of the Striant system. Men using this form of TRT must be informed about the potential dental health implications and the importance of adhering to a strict oral hygiene regimen. Compliance with both the TRT and oral care protocols is essential to ensure the benefits of testosterone replacement are not overshadowed by dental complications.

Conclusion

The two-year study on the impact of the Striant Testosterone Buccal System on dental health in American males reveals that while the system is effective for TRT, it necessitates heightened attention to oral hygiene. Although there was no significant increase in severe dental issues, the slight increase in plaque buildup highlights the need for careful oral care. Dental professionals and patients alike must work together to ensure that the benefits of Striant are maximized while maintaining optimal oral health. As TRT continues to be a vital treatment for many American males, ongoing research and education will be crucial in refining these practices.

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